
This hearty Mississippi Pot Roast has been my secret weapon for family dinners for years. With just five simple ingredients and a slow cooker, this melt-in-your-mouth roast transforms into a meal that will have everyone asking for seconds.
I first discovered this recipe during a particularly busy season when I needed more hands-off meals. After the first bite, my husband declared it the best pot roast he’d ever eaten, and now it’s requested at least twice a month in our home.
Ingredients
- Chuck roast: 3 to 4 pounds for the perfect balance of fat and meat that becomes incredibly tender after slow cooking
- Ranch dressing mix packet: adds a savory herb blend that perfectly seasons the meat without any extra measuring
- Au jus gravy mix packet: creates a rich base for the gravy that forms while cooking
- Butter: quarter cup adds richness and helps create the most luxurious sauce
- Pepperoncini peppers: 4 to 5 adds a mild tanginess that cuts through the richness without making it spicy
Step-by-Step Instructions
- Prepare the Roast:
- Place your chuck roast in the slow cooker insert making sure it’s centered and has room around it. No need to sear beforehand; the slow cooking will develop plenty of flavor. The beauty of this recipe is its simplicity.
- Season Generously:
- Sprinkle the entire ranch dressing packet evenly over the top of the roast. Follow by sprinkling the au jus mix over that, creating a flavorful crust that will slowly incorporate into the meat as it cooks.
- Add Flavor Enhancers:
- Place the pepperoncini peppers strategically around the top of the roast. These mild peppers infuse a subtle tangy flavor throughout the cooking process. Then add the butter, cutting it into smaller pieces and placing them on top of the roast.
- Set It and Forget It:
- Cover the slow cooker and set to low heat for a full 8 hours. Resist the urge to lift the lid, which releases essential heat and moisture. The magic happens when you let it cook undisturbed.
- Shred and Serve:
- After 8 hours, the roast will be incredibly tender. Gently shred the meat using two forks, removing any large pieces of fat. Mix the meat with the rich gravy that’s formed and serve over your choice of starch.

The pepperoncini peppers are actually my favorite part of this recipe. While they might seem like an unusual addition, they provide the perfect hint of acidity that balances the rich, buttery flavors of the sauce. My grandmother was initially skeptical, but now she adds extra peppers to her portion.
Storage and Leftovers
This Mississippi Pot Roast shines as leftovers and may actually taste even better the next day as the flavors continue to meld. Store the meat and gravy together in an airtight container in the refrigerator for up to 4 days. For longer storage, freeze portions in freezer-safe containers for up to 3 months. Thaw overnight in the refrigerator before reheating gently on the stovetop or in the microwave with a splash of beef broth if needed to maintain moisture.
Easy Variations
While the classic recipe is perfect as is, there are several ways to customize your Mississippi Pot Roast based on preferences or what you have on hand. If you can’t find au jus mix, brown gravy mix makes a good substitute. For those watching sodium intake, look for low-sodium versions of the seasoning packets. You can also add vegetables like quartered potatoes, baby carrots, or pearl onions to the slow cooker during the last 1-2 hours of cooking time to create a complete one-pot meal.
Serving Suggestions
The rich buttery gravy from this pot roast pairs particularly well with starches that can soak it up. Mashed potatoes are the classic choice, but egg noodles, rice, or crusty bread are excellent alternatives. For a lower-carb option, serve over cauliflower mash or with a side of roasted vegetables. I like to add a bright, simple side salad with a vinaigrette dressing to cut through the richness of the main dish.
Frequently Asked Questions
- → Can I use a different cut of meat for this dish?
Yes, you can substitute chuck roast with brisket or rump roast, but chuck roast is ideal for its tenderness when slow-cooked.
- → Do I need to add water or broth?
No, the roast produces enough liquid while cooking, so additional water or broth is unnecessary.
- → Can I add vegetables to the dish?
Absolutely! Add quartered potatoes and baby carrots during the last 1-2 hours of cooking for a complete meal.
- → How spicy are the pepperoncini peppers?
Pepperoncini peppers add a mild tangy flavor with minimal heat, making the dish flavorful without being overly spicy.
- → How should I serve Mississippi Pot Roast?
Serve it over mashed potatoes, rice, or egg noodles for a hearty and satisfying meal.