Buffalo Chicken Ranch Lasagna

This Buffalo Chicken Lasagna combines two beloved flavors - spicy buffalo sauce and creamy ranch - into a comforting, crowd-pleasing dish that brings a twist to traditional Italian lasagna. The layers of tender pasta, zesty chicken, and three types of cheese create an irresistible meal that's perfect for dinner, game day gatherings, or anytime you're craving something bold and satisfying.

I first created this recipe when hosting friends for a football Sunday, and it's been requested at every gathering since. The combination of spicy buffalo sauce with cooling ranch and melty cheese creates that perfect balance that keeps everyone coming back for seconds.

Ingredients

• Lasagna noodles: the foundation of any great lasagna that provides the perfect structure for layering all those delicious ingredients
• Shredded chicken: saves time by using rotisserie chicken or meal prepped chicken from earlier in the week
• Buffalo sauce: the star flavor that brings heat and tanginess to transform traditional lasagna
• Ranch dressing: cools the spice while adding creamy richness that balances the buffalo kick perfectly
• Ricotta cheese: creates a velvety layer that mellows the spice and adds classic lasagna texture
• Egg: helps bind the ricotta layer so it stays together when slicing
• Three cheese blend: mozzarella for stretch, cheddar for sharpness, and optional blue cheese for authentic buffalo wing flavor
• Spices: garlic powder, onion powder, salt and pepper enhance the flavor without competing with the buffalo profile
• Green onions: add a fresh pop of color and mild onion flavor to finish the dish

Step-by-Step Instructions

Preheat and Prep:

Set your oven to 375°F and take time to properly grease your baking dish to prevent sticking. This ensures the lasagna will release cleanly when serving. While the oven heats, you can prepare your components.

Buffalo Chicken Mixture:

In a large bowl, thoroughly combine the shredded chicken with buffalo sauce and ranch dressing. Make sure every piece of chicken is coated for consistent flavor throughout the dish. The sauce should be well incorporated but not overly soggy.

Ricotta Mixture:

In a separate bowl, combine the ricotta with a beaten egg and seasonings. The egg helps this layer set properly while baking, and the seasonings infuse the mild cheese with complementary flavors. Whisk until completely smooth with no lumps.

First Layer:

Begin with a thin layer of buffalo chicken mixture on the bottom of your baking dish. This prevents the noodles from sticking and adds flavor to every bite. Spread it evenly, reaching all corners of the dish.

Building Layers:

Place three cooked lasagna noodles side by side over the sauce. Spread one third of the ricotta mixture over the noodles, then add one third of the buffalo chicken mixture. Sprinkle generously with the cheese blend. Repeat this layering process two more times.

Final Layer:

For the top layer, place the last three noodles, then cover with the remaining buffalo chicken mixture. Finish with a generous topping of all three cheeses, making sure to cover the entire surface for that perfect golden crust.

Baking Strategy:

Cover tightly with foil for the first 25 minutes to trap steam and cook the layers together. Then remove the foil for the final 10 minutes to allow the cheese to bubble and develop those irresistible browned spots.

Resting Period:

Allow the finished lasagna to rest for 10 full minutes before slicing. This crucial step lets the layers set and prevents the filling from running when cut. Finish with fresh green onions just before serving.

Save This

The blue cheese in this recipe is my secret weapon. Though optional, it adds that authentic buffalo wing experience that transforms this from a good lasagna into something truly memorable. When I first added it, my buffalo-wing-obsessed husband declared it was the best dinner I'd ever made.

Common Queries

→ How spicy is this lasagna?

The lasagna has a moderate spice level due to the Buffalo sauce. For a milder taste, you can mix Buffalo sauce with marinara or use a milder sauce entirely.

→ Can I prepare this dish ahead of time?

Absolutely! Assemble the lasagna and refrigerate it for up to 24 hours before baking. Let it sit at room temperature for 15 minutes before placing it in the oven.

→ Can I substitute any ingredients?

Yes! You can replace blue cheese with extra cheddar for a milder flavor or swap ranch for a favorite creamy dressing of your choice.

→ What sides pair well with this dish?

Serve the lasagna with a side of garlic bread or a crisp green salad to complement its rich flavors.

→ How should I store the leftovers?

Store any leftovers in an airtight container in the refrigerator for up to 3 days. Reheat in the oven or microwave before serving.